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1

What is the main mechanism of tramadol?

Minami, Kouichiro, Ogata, Junichi, Uezono, Yasuhito

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2015

Language:

english

File:

PDF, 528 KB

english, 2015

2

Carvacrol inhibits the neuronal voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.3, Nav1.7, and Nav1.8 expressed in Xenopus oocytes with different potencies

Horishita, Takafumi, Ogata, Yuichi, Horishita, Reiko, Fukui, Ryo, Moriwaki, Kuniaki, Ueno, Susumu, Yanagihara, Nobuyuki, Uezono, Yasuhito, Sudo, Yuka, Minami, Kouichiro

Journal:

Journal of Pharmacological Sciences

Year:

2020

Language:

english

File:

PDF, 2.41 MB

english, 2020

3

An active metabolite of carbamazepine, carbamazepine-10,11-epoxide, inhibits ion channel-mediated catecholamine secretion in cultured bovine adrenal medullary cells

Reiji Yoshimura, N. Yanagihara, Takeshi Terao, Kouichiro Minami, Yumiko Toyohira, Susumu Ueno, Yasuhito Uezono, Kazuhiko Abe, Futoshi Izumi

Journal:

Psychopharmacology

Year:

1998

Language:

english

File:

PDF, 357 KB

english, 1998

4

Inhibition by Pregnenolone Sulphate, a Metabolite of the Neurosteroid Pregnenolone, of Voltage-Gated Sodium Channels Expressed in Xenopus Oocytes

Horishita, Takafumi, Ueno, Susumu, Yanagihara, Nobuyuki, Sudo, Yuka, Uezono, Yasuhito, Okura, Dan, Sata, Takeyoshi

Journal:

Journal of Pharmacological Sciences

Year:

2012

Language:

english

File:

PDF, 299 KB

english, 2012

5

Possible involvement of the peripheral Mu-opioid system in antinociception induced by bergamot essential oil to allodynia after peripheral nerve injury

Komatsu, Takaaki, Katsuyama, Soh, Uezono, Yasuhito, Sakurada, Chikai, Tsuzuki, Minoru, Hamamura, Kengo, Bagetta, Giacinto, Sakurada, Shinobu, Sakurada, Tsukasa

Journal:

Neuroscience Letters

Year:

2018

Language:

english

File:

PDF, 546 KB

english, 2018

6

A novel strategy for treatment of cancer cachexia targeting xanthine oxidase in the brain

Uzu, Miaki, Nonaka, Miki, Miyano, Kanako, Sato, Hiromi, Kurebayashi, Nagomi, Yanagihara, Kazuyoshi, Sakurai, Takashi, Hisaka, Akihiro, Uezono, Yasuhito

Journal:

Journal of Pharmacological Sciences

Year:

2019

Language:

english

File:

PDF, 853 KB

english, 2019

7

Desensitization of GABAB receptor signaling by formation of protein complexes of GABAB2 subunit with GRK4 or GRK5

Masato Kanaide, Yasuhito Uezono, Masanori Matsumoto, Minoru Hojo, Yuko Ando, Yuka Sudo, Koji Sumikawa, Kohtaro Taniyama

Journal:

Journal of Cellular Physiology

Year:

2007

Language:

english

File:

PDF, 390 KB

english, 2007

8

Down-Regulation of the Noradrenaline Transporter by Interferon-α in Cultured Bovine Adrenal Medullary Cells

Yumiko Toyohira, Nobuyuki Yanagihara, Kouichiro Minami, Susumu Ueno, Yasuhito Uezono, Eiichi Tachikawa, Yukiko Kondo, Takeshi Kashimoto, Futoshi Izumi

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 692 KB

english, 1998

9

Pituitary Adenylate Cyclase-Activating Polypeptide Causes Ca2+ Release from Ryanodine/Caffeine Stores Through a Novel Pathway Independent of Both Inositol Trisphosphates and Cyclic AMP in Bovine Adrenal Medullary Cells

Keiko Tanaka, Izumi Shibuya, Yasuhito Uezono, Yoichi Ueta, Yumiko Toyohira, Nobuyuki Yanagihara, Futoshi Izumi, Tomio Kanno, Hiroshi Yamashita

Journal:

Journal of Neurochemistry

Year:

1998

Language:

english

File:

PDF, 1013 KB

english, 1998

10

Possible involvement of β-endorphin in a loss of the coordinated balance of μ-opioid receptors trafficking processes by fentanyl

Satoshi Imai, Yuka Sudo, Atsushi Nakamura, Ayumi Ozeki, Megumi Asato, Minoru Hojo, Lakshmi A. Devi, Naoko Kuzumaki, Tsutomu Suzuki, Yasuhito Uezono, Minoru Narita

Journal:

Year:

2011

Language:

english

File:

PDF, 418 KB

english, 2011

11

The effects of the neurosteroids: pregnenolone, progesterone and dehydroepiandrosterone on muscarinic receptor-induced responses inXenopusoocytes expressing M1and M3receptors

Takafumi Horishita, Kouichiro Minami, Yasuhito Uezono, Munehiro Shiraishi, Junichi Ogata, Takashi Okamoto, Tadanori Terada, Takeyoshi Sata

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2005

Language:

english

File:

PDF, 220 KB

english, 2005

12

Selective blockade of nicotinic acetylcholine receptors by pimobendan, a drug for the treatment of heart failure: reduction of catecholamine secretion and synthesis in adrenal medullary cells

Yumiko Toyohira, Tatsuhiko Kubo, Miyabi Watanabe, Yasuhito Uezono, Susumu Ueno, Koji Shinkai, Masato Tsutsui, Futoshi Izumi, Nobuyuki Yanagihara

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2005

Language:

english

File:

PDF, 178 KB

english, 2005

13

Dexmedetomidine inhibits muscarinic type 3 receptors expressed inXenopusoocytes and muscarine-induced intracellular Ca2+elevation in cultured rat dorsal root ganglia cells

Atsushi Takizuka, Kouichiro Minami, Yasuhito Uezono, Takafumi Horishita, Toru Yokoyama, Munehiro Shiraishi, Takeshi Sakurai, Akio Shigematsu, Yoichi Ueta

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2007

Language:

english

File:

PDF, 283 KB

english, 2007

14

Effects of sevoflurane on voltage-gated sodium channel Nav1.8, Nav1.7, and Nav1.4 expressed inXenopusoocytes

Toru Yokoyama, Kouichiro Minami, Yuka Sudo, Takafumi Horishita, Junichi Ogata, Toshihiko Yanagita, Yasuhito Uezono

Journal:

Journal of Anesthesia

Year:

2011

Language:

english

File:

PDF, 294 KB

english, 2011

15

Sequential changes in transforming growth factor (TGF)-β1 concentration in synovial fluid and mRNA expression of TGF-β1 receptors in chondrocytes after immobilization of rabbit knees

Ryuji Okazaki, Akinori Sakai, Yasuhito Uezono, Akira Ootsuyama, Naoki Kunugita, Toshitaka Nakamura, Toshiyuki Norimura

Journal:

Journal of Bone and Mineral Metabolism

Year:

2001

Language:

english

File:

PDF, 218 KB

english, 2001

16

Possible involvement of prolonging spinal µ-opioid receptor desensitization in the development of antihyperalgesic tolerance to µ-opioids under a neuropathic pain-like state

Minoru Narita, Satoshi Imai, Atsushi Nakamura, Ayumi Ozeki, Megumi Asato, Mahardian Rahmadi, Yuka Sudo, Minoru Hojo, Yasuhito Uezono, Lakshmi A. Devi, Naoko Kuzumaki, Tsutomu Suzuki

Journal:

Addiction Biology

Year:

2012

Language:

english

File:

PDF, 773 KB

english, 2012

17

Evidence that multiple P2X purinoceptors are functionally expressed in rat supraoptic neurones

Izumi Shibuya, Keiko Tanaka, Yukio Hattori, Yasuhito Uezono, Nobuya Harayama, Jun Noguchi, Yoichi Ueta, Futoshi Izumi, Hiroshi Yamashita

Journal:

The Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 1.53 MB

english, 1999

18

Sodium/Proton Exchange in Cultured Bovine Adrenal Medullary Cells

Nobuyuki Yanagihara, Kenji Yokota, Hideyuki Kobayashi, Akihiko Wada, Yasuhito Uezono, Futoshi Izumi

Journal:

Journal of Neurochemistry

Year:

1990

Language:

english

File:

PDF, 625 KB

english, 1990

19

Lysophosphatidic acid-LPA1 receptor–Rho–Rho kinase-induced up-regulation of Nav1.7 sodium channel mRNA and protein in adrenal chromaffin cells: enhancement of 22Na+ influx, 45Ca2+ influx and catecholamine secretion

Toyoaki Maruta, Toshihiko Yanagita, Kiyotaka Matsuo, Yasuhito Uezono, Shinya Satoh, Takayuki Nemoto, Norie Yoshikawa, Hideyuki Kobayashi, Mayumi Takasaki, Akihiko Wada

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 684 KB

english, 2008

20

Inhibitory Effects of Ethanol on Rat Mesangial Cell Proliferation via Protein Kinase C Pathway

Kayoko Segawa, Kouichiro Minami, Yasuhito Uezono, Munehiro Shiraishi, Akio Shigematsu

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2002

Language:

english

File:

PDF, 115 KB

english, 2002

21

Serum Deprivation-Induced Upregulation of Voltage-Dependent Sodium Channels in Adrenal Chromaffin Cells : Selective Involvement of Extracellular Signal-Regulated Kinase Pathway

TOSHIHIKO YANAGITA, HIDEYUKI KOBAYASHI, HIROKI YOKOO, TOMOKAZU SAITOH, SHIN-ICHI MINAMI, SEIJI SHIRAISHI, YASUHITO UEZONO, AKIHIKO WADA

Journal:

Annals of the New York Academy of Sciences

Year:

2002

File:

PDF, 734 KB

2002

22

Adrenomedullin inhibits spontaneous and bradykinin-induced but not oxytocin- or prostaglandin F2α-induced periodic contraction of rat uterus

Toshihiko Yanagita, Ryuichi Yamamoto, Takashi Sugano, Hideyuki Kobayashi, Yasuhito Uezono, Hiroki Yokoo, Seiji Shiraishi, Shin-ichi Minami, Akihiko Wada

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 140 KB

english, 2000

23

Heterogeneous increases of cytoplasmic calcium: distinct effects on down-regulation of cell surface sodium channels and sodium channel subunit mRNA levels

Seiji Shiraishi, Izumi Shibuya, Yasuhito Uezono, Hiroki Yokoo, Yumiko Toyohira, Ryuichi Yamamoto, Toshihiko Yanagita, Hideyuki Kobayashi, Akihiko Wada

Journal:

British Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 305 KB

english, 2001

24

Inhibitory effects of tramadol on nicotinic acetylcholine receptors in adrenal chromaffin cells and in Xenopus oocytes expressing α7 receptors

Munehiro Shiraishi, Kouichiro Minami, Yasuhito Uezono, Nobuyuki Yanagihara, Akio Shigematsu, Izumi Shibuya

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 230 KB

english, 2002

25

GABAB receptors do not internalize after baclofen treatment, possibly due to a lack of β-arrestin association: Study with a real-time visualizing assay

Yuka Sudo, Minoru Hojo, Yuko Ando, Masafumi Takada, Hiroaki Murata, Shinji Kurata, Noriyuki Nishida, Yasuhito Uezono

Journal:

Year:

2012

Language:

english

File:

PDF, 2.01 MB

english, 2012

26

Changes in the melanocortin receptors in the hypothalamus of a rat model of cancer cachexia

Masami Suzuki, Minoru Narita, Maho Ashikawa, Sadayoshi Furuta, Motohiro Matoba, Hiroki Sasaki, Kazuyoshi Yanagihara, Kiyoshi Terawaki, Tsutomu Suzuki, Yasuhito Uezono

Journal:

Year:

2012

Language:

english

File:

PDF, 915 KB

english, 2012

27

Veratridine causes the Ca2+-dependent increase in diacylglycerol formation and translocation of protein kinase C to membranes in cultured bovine adrenal medullary cells

Yasuhito Uezono, Akihiko Wada, Nobuyuki Yanagihara, Hideyuki Kobayashi, Tsunetaka Mizuki, Takeshi Terao, Yoshiro Koda, Futoshi Izumi

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1992

Language:

english

File:

PDF, 677 KB

english, 1992

28

Veratridine-induced phosphorylation and activation of tyrosine hydroxylase, and synthesis of catecholamines in cultured bovine adrenal medullary cells

Yasuhito Uezono, Nobuyuki Yanagihara, Akihiko Wada, Yoshiro Koda, Kenji Yokota, Hideyuki Kobayashi, Futoshi Izumi

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1989

Language:

english

File:

PDF, 862 KB

english, 1989

29

Conotoxin GIIIA: selective inhibition of22Na influx via voltage-dependent Na channels in adrenal medullary cells

Akihiko Wada, Yasuhito Uezono, Masahide Arita, Yuchio Yanagawa, Mei Satake, Futoshi Izumi

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1990

Language:

english

File:

PDF, 530 KB

english, 1990

30

Stimulatory effects of brain natriuretic peptide on cyclic GMP accumulation and tyrosine hydroxylase activity in cultured bovine adrenal medullary cells

Nobuyuki Yanagihara, Masahiro Okazaki, Takeshi Terao, Yasuhito Uezono, Akihiko Wada, Futoshi Izumi

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1991

Language:

english

File:

PDF, 1.02 MB

english, 1991

31

Inhibition by vecuronium of carbachol-induced influx of22Na2+,45Ca2+and secretion of catecholamines in cultured bovine adrenal medullary cells

Akihiko Wada, Masahide Arita, Hiroshi Takara, Koji Sumikawa, Yasuhito Uezono, Futoshi Izumi

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1989

Language:

english

File:

PDF, 507 KB

english, 1989

32

Allyl isothiocyanates and cinnamaldehyde potentiate miniature excitatory postsynaptic inputs in the supraoptic nucleus in rats

Toru Yokoyama, Toyoaki Ohbuchi, Takeshi Saito, Yuka Sudo, Hiroaki Fujihara, Kouichiro Minami, Toshihisa Nagatomo, Yasuhito Uezono, Yoichi Ueta

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

33

Characterization and functional role of leptin receptor in bovine adrenal medullary cells

Nobuyuki Yanagihara, Kensuke Utsunomiya, Tat Beng Cheah, Hideyasu Hirano, Koji Kajiwara, Koji Hara, Ei’ichiro Nakamura, Yumiko Toyohira, Yasuhito Uezono, Susumu Ueno, Futoshi Izumi

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 376 KB

english, 2000

34

Inhibition of the norepinephrine transporter function in cultured bovine adrenal medullary cells by bisphenol A

Yumiko Toyohira, Kensuke Utsunomiya, Susumu Ueno, Kouichiro Minami, Yasuhito Uezono, Reiji Yoshimura, Masato Tsutsui, Futoshi Izumi, Nobuyuki Yanagihara

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 156 KB

english, 2003

35

Down-regulation of cell surface insulin receptors by sarco(endo)plasmic reticulum Ca2+-ATPase inhibitor in adrenal chromaffin cells

Seiji Shiraishi, Ryuichi Yamamoto, Toshihiko Yanagita, Hiroki Yokoo, Hideyuki Kobayashi, Yasuhito Uezono, Akihiko Wada

Journal:

Year:

2001

Language:

english

File:

PDF, 382 KB

english, 2001

36

Transmural compression-induced proliferation and DNA synthesis through activation of a tyrosine kinase pathway in rat astrocytoma RCR-1 cells

Yosuke Oishi, Yasuhito Uezono, Nobuyuki Yanagihara, Futoshi Izumi, Toshitaka Nakamura, Katsumi Suzuki

Journal:

Year:

1998

Language:

english

File:

PDF, 263 KB

english, 1998

37

Adrenomedullin increases intracellular Ca2+ and inositol 1,4,5-trisphosphate in human oligodendroglial cell line KG-1C

Yasuhito Uezono, Izumi Shibuya, Yoko Ueda, Keiko Tanaka, Yosuke Oishi, Nobuyuki Yanagihara, Susumu Ueno, Yumiko Toyohira, Toshitaka Nakamura, Hiroshi Yamashita, Futoshi Izumi

Journal:

Year:

1998

Language:

english

File:

PDF, 260 KB

english, 1998

38

Activation of extracellular signal-regulated kinases is essential for pressure-induced proliferation of vascular smooth muscle cells

Yuki Tsuda, Masahiro Okazaki, Yasuhito Uezono, Akihiko Osajima, Hiroaki Kato, Haruhito Okuda, Yosuke Oishi, Akira Yashiro, Yasuhide Nakashima

Journal:

European Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 340 KB

english, 2002

39

Involvement of cholinergic neurons in orexin-induced contraction of guinea pig ileum

Katsuhisa Matsuo, Muneshige Kaibara, Yasuhito Uezono, Hideki Hayashi, Kohtaro Taniyama, Yoshibumi Nakane

Journal:

European Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 128 KB

english, 2002

40

Enhancement by Baclofen of the Gs-Coupled Receptor-Mediated cAMP Production inXenopusOocytes Expressing Rat Brain Cortex Poly (A)+RNA: A Role of G-Protein βγ Subunits

Yasuhito Uezono, Yoko Ueda, Susumu Ueno, Izumi Shibuya, Nobuyuki Yanagihara, Yumiko Toyohira, Hiroshi Yamashita, Futoshi Izumi

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 141 KB

english, 1997

41

Function of the Rat Calcitonin Receptors, C1a and C1b, Expressed inXenopusOocytes

Masanori Matsumoto, Muneshige Kaibara, Yasuhito Uezono, Futoshi Izumi, Koji Sumikawa, Patrick M. Sexton, Kohtaro Taniyama

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 123 KB

english, 1998

42

Function of the Rat Calcitonin Receptors, C1a and C1b, Expressed inXenopus Oocytes,: Volume 242, Number 3 (1998), pages 484–491:

Masanori Matsumoto, Muneshige Kaibara, Yasuhito Uezono, Futoshi Izumi, Koji Sumikawa, Patrick M. Sexton, Kohtaro Taniyama

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 44 KB

english, 1998

43

Cloning and Tissue Distribution of Novel Splice Variants of the Rat GABABReceptor

Shojiro Isomoto, Muneshige Kaibara, Yasuko Sakurai-Yamashita, Yuji Nagayama, Yasuhito Uezono, Katsusuke Yano, Kohtaro Taniyama

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 563 KB

english, 1998

44

Activation of tyrosine hydroxylase by micromolar concentrations of calcium in digitonin-permeabilized adrenal medullary cells

Nobuyuki Yanagihara, Yasuhito Uezono, Yoshiro Koda, Akihiko Wada, Futoshi Izumi

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 424 KB

english, 1987

45

Protein kinase C subtypes in tissues derived from neural crest

Yoshiro Koda, Hideyuki Kobayashi, Tsunetaka Mizuki, Masahiro Okazaki, Yasuhito Uezono, Nobuyuki Yanagihara, Akihiko Wada, Futoshi Izumi

Journal:

Year:

1990

Language:

english

File:

PDF, 282 KB

english, 1990

46

C-type natriuretic peptide increases cyclic GMP in rat cerebral microvessels in primary culture

Hideyuki Kobayashi, Susumu Ueno, Masato Tsutsui, Masahiro Okazaki, Yasuhito Uezono, Nobuyuki Yanagihara, Tomoaki Yuhi, Futoshi Izumi

Journal:

Year:

1994

Language:

english

File:

PDF, 773 KB

english, 1994

47

Pituitary adenylate cyclase-activating polypeptides (PACAPs) increase cAMP in rat cerebral microvessels

Hideyuki Kobayashi, Yasuhito Uezono, Susumu Ueno, Futoshi Izumi

Journal:

Year:

1994

Language:

english

File:

PDF, 257 KB

english, 1994

48

Adrenomedullin increases cyclic AMP more potently than CGRP and amylin in rat renal tubular basolateral membranes

Akihiko Osajima, Yoshinobu Mutoh, Yasuhito Uezono, Masaru Kawamura, Futoshi Izumi, Masayuki Takasugi, Akio Kuroiwa

Journal:

Year:

1995

Language:

english

File:

PDF, 401 KB

english, 1995

49

G-protein-coupled receptors as targets for anesthetics

Kouichiro Minami, Yasuhito Uezono

Journal:

International Congress Series

Year:

2005

Language:

english

File:

PDF, 77 KB

english, 2005

50

Activation of the neurokinin-1 receptor in rat spinal astrocytes induces Ca2+ release from IP3-sensitive Ca2+ stores and extracellular Ca2+ influx through TRPC3

Kanako Miyano, Norimitsu Morioka, Tatsuhiko Sugimoto, Seiji Shiraishi, Yasuhito Uezono, Yoshihiro Nakata

Journal:

Neurochemistry International

Year:

2010

Language:

english

File:

PDF, 874 KB

english, 2010

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